| 翻訳と辞書 |
| Walleye epidermal hyperplasia virus ： ウィキペディア英語版 |
Walleye epidermal hyperplasia virus
Walleye epidermal hyperplasia virus is a retrovirus classified under, Epsilonretroviruses, a recent genus addition to the family of Retroviridae.〔(Epsilonretrovirus ), Viral Zone〕 There are three genome sequenced and identified exogenous retroviruses of this genus which include two known types (WEHV-1 and WEHV-2) associated with walleye epidermal hyperplasia disease. Both viral types are confirmed to be the causative agents of the neoplastic condition in the freshwater fish species, the North American Walleye ''(Stizostedion vitreum)''. The specific association of retroviral infection with proliferative lesions in fish is based on the presence of retrovirus-like particles (observed via electron microscopy) and reverse transcriptase activity (using reverse transcriptase polymerase chain reaction techniques) from neoplastic tissue. Although both virus types have been observed in lesions of diseased fish, each cell of the infected tissue is host to a specific virus. Transmission studies have also shown that WEHV-2 has been the more proliferative agent of the condition as compared to WEHV-1.
==Phylogeny==
Phylogenetic analysis of the three confirmed Epsilonretroviruses shows they are related. After cloning techniques, sequence analysis determined that WEHV-1 and WEHV-2 are similar in size and share 95% amino acid identity in the ''pol'' region of reverse transcriptase. This finding suggests that they are different strains of the same virus or likely distinct species. The two types of WEHV also share over 80% of their amino acid sequence with the third member of the epsilonretrovirus genus. Included in this analysis was the observation of a homologous genomic organization in all three Epsilonretroviruses.
抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』
■ウィキペディアで「Walleye epidermal hyperplasia virus」の詳細全文を読む
スポンサード リンク
| 翻訳と辞書 : 翻訳のためのインターネットリソース |
Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.
|
|